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June 21, 2020 03:34 pm

Quest for a Vaccine: Oxford Reaches Final Large-Scale Trial

An anonymous reader quotes The Washington Post:In the global race for a coronavirus vaccine, more than 100 labs, universities and drug companies have started off on experimental missions. But just 11 candidate vaccines, according to the World Health Organization, have reached the stage of clinical testing. The WHO says that only Oxford University's vaccine has reached what is known as Phase 3, the final and largest-scale trial... "There is quite a strong probability that the vaccine will work," said Walter Ricciardi, the World Health Organization's Italian government adviser. But the vaccine is far from a sure thing, according to experts. It might not work, or it might give immunity to only some of those who are injected. Even once a vaccine makes it to market, it remains unknown whether it will offer long-term protection, or only for a year or two. The world will ultimately need more than one vaccine anyway, as demand will soar beyond what any one company could produce. "The expectation is that we will have a protective vaccine. Probably more than one," said Antonio Cassone, the former head of the infectious-disease department at Italy's national health institute. "But nobody will know at that time how long the protection will last. We don't know the antibody duration. This will be yet another jump into the unknown." A Chinese biotech firm has reported encouraging results in early-stage clinical trials and is also among the front-runners to crack the vaccine code. The article adds that Oxford's vaccine "proved effective and safe with rhesus monkeys during the earliest stage of experimentation."

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