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February 29, 2020 11:34 pm

What Happens After 550 Times the Usual Dose of LSD?

"From the Journal of Studies on Alcohol and Drugs comes three case studies on people who benefited from LSD overdoses including one woman who took a dose of 55 milligrams of pure powdered LSD," writes clovis (Slashdot reader #4,684). CNN reports:The 49-year-old woman, known as CB, had contracted Lyme disease in her early 20s, which damaged her feet and ankles and left her in "significant pain." In September 2015, she took 55 milligrams of what she believed was cocaine but was actually "pure LSD in powder form." The authors defined a normal recreational dose as 100 micrograms -- equal to 0.1 milligrams. The woman blacked out and vomited frequently for the next 12 hours but reported feeling "pleasantly high" for the 12 hours after that -- still vomiting, but less often. According to her roommate, she sat mostly still in a chair, either with her eyes open or rolled back, occasionally speaking random words. Ten hours later, she was able to hold a conversation and "seemed coherent." Her foot pain was gone the next day and she stopped using morphine for five days. While the pain returned, she was able to control it with a lower dose of morphine and a microdose of LSD every three days. After more than two years, in January 2018, she stopped using both morphine and LSD and reported no withdrawal symptoms, although the case report said she did experience an increase in anxiety, depression and social withdrawal.

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