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October 14, 2019 07:30 pm

A Code Glitch May Have Caused Errors In More Than 100 Published Studies

Scientists have uncovered a glitch in a piece of code that could have yielded incorrect results in over 100 published studies that cited the original paper. From a report: The glitch caused results of a common chemistry computation to vary depending on the operating system used, causing discrepancies among Mac, Windows, and Linux systems. The researchers published the revelation and a debugged version of the script, which amounts to roughly 1,000 lines of code, last week in the journal Organic Letters. "This simple glitch in the original script calls into question the conclusions of a significant number of papers on a wide range of topics in a way that cannot be easily resolved from published information because the operating system is rarely mentioned," the new paper reads. "Authors who used these scripts should certainly double-check their results and any relevant conclusions using the modified scripts in the [supplementary information]." Yuheng Luo, a graduate student at the University of Hawai'i at Manoa, discovered the glitch this summer when he was verifying the results of research conducted by chemistry professor Philip Williams on cyanobacteria. The aim of the project was to "try to find compounds that are effective against cancer," Williams said.

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