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May 4, 2020 09:10 pm

Scientists Create Antibody That Defeats Coronavirus in Lab

Scientists created a monoclonal antibody that can defeat the new coronavirus in the lab, an early but promising step in efforts to find treatments and curb the pandemic's spread. From a report: The experimental antibody has neutralized the virus in cell cultures. While that's early in the drug development process -- before animal research and human trials -- the antibody may help prevent or treat Covid-19 and related diseases in the future, either alone or in a drug combination, according to a study [PDF] published Monday in the journal Nature Communications. More research is needed to see whether the findings are confirmed in a clinical setting and how precisely the antibody defeats the virus, Berend-Jan Bosch of Utrecht University in the Netherlands and colleagues wrote in the paper. The antibody known as 47D11 targets the spike protein that gives the new coronavirus a crown-like shape and lets it enter human cells. In the Utrecht experiments, it didn't just defeat the virus responsible for Covid-19 but also a cousin equipped with similar spike proteins, which causes Severe Acute Respiratory Syndrome, or SARS.

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