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February 19, 2022 03:34 pm

Ivermectin Doesn't Prevent Severe COVID-19, New Study Finds

UPI reports on the results of a new randomized-controlled trial of ivermectin, the "gold standard" of medical research. UPI reports that treatment with ivermectin "failed to prevent patients with mild to moderate COVID-19 from progressing to serious illness, a study published Friday by JAMA Internal Medicine found."Of 241 patients in the study with mild to moderate symptoms treated with the veterinary medication, 52, or 22% developed severe COVID-19, the data showed. Meanwhile, 43 of 249 patients, or 17%, who received "standard" treatment, including corticosteroids and, in a handful of cases, other experimental drugs, progressed to serious illness from the virus, the researchers said. "Essentially, our study findings have dismissed the notion of ivermectin being a 'miracle drug' against COVID-19," study co-author Dr. Steven Chee Loon Lim told UPI in an email.... In addition, study participants treated with ivermectin reported more side effects than those given other drugs, Lim said. This "raises concerns about the widespread use of this drug," he said.... 14 of the ivermectin patients developed severe diarrhea and four suffered potentially life-threatening kidney damage, the researchers said. The new study also examined whether patients had to go on a ventilator, needed intensive care or died from their infections — and discovered "there were no significant differences between groups." And the researchers' study also points out that two additional randomized clinical trials conducted in 2021 also "found no significant effect of ivermectin on symptom resolution and hospitalization rates." UPI now quotes Dr. Lim as saying Friday that despite early hopes for ivermectin, "large and well-designed randomized clinical trials, including ours, have consistently shown that ivermectin offered little or no significant clinical benefits. "I believe the findings in our study will likely 'close the door' on the use of ivermectin as a treatment for COVID-19."

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