Siamese cats are heatmaps of themselves

Siamese cats are walking heatmaps. Their characteristic coloration results from a delightful mutation (maybe I should call it a mew-tation) in tyrosinase, an enzyme that makes melanin. A deleted cytosine amino acid causes a frameshift mutation. The result? Tyrosinase in Siamese cats is particularly sensitive to temperature, denaturing at normal body temperature. — Read the rest