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April 24, 2020 03:32 pm

Researchers Cut Chloroquine Study Short Over Safety Concerns, Citing a 'Primary Outcome' of Death

Citing a "primary outcome" of death, researchers cut short a study testing anti-malaria drug chloroquine as a potential treatment for Covid-19 after some patients developed irregular heart rates and nearly two dozen of them died after taking doses of the drug daily. From a report: Scientists say the findings, published Friday in the peer-reviewed Journal of the American Medical Association, should prompt some degree of skepticism from the public toward enthusiastic claims about and perhaps "serve to curb the exuberant use" of the drug, which has been touted by President Donald Trump as a potential "game-changer" in the fight against the coronavirus. Chloroquine gained widespread international attention following two small studies, including one with 36 Covid-19 patients published March 17 in France, found that most patients taking the drug cleared the coronavirus from their system a lot faster than the control group. The JAMA report said those trials didn't meet the publishing society's standards.

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