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January 30, 2020 03:30 am

Lab-Grown Heart Muscles Have Been Transplanted Into a Human For the First Time

An anonymous reader quotes a report from ScienceAlert: On Monday, researchers from Japan's Osaka University announced the successful completion of a first-of-its-kind heart transplant. Rather than replacing their patient's entire heart with a new organ, these researchers placed degradable sheets containing heart muscle cells onto the heart's damaged areas -- and if the procedure has the desired effect, it could eventually eliminate the need for some entire heart transplants. To grow the heart muscle cells, the team started with induced pluripotent stem (iPS) cells. These are stem cells that researchers create by taking an adult's cells -- often from their skin or blood -- and reprogramming them back into their embryonic-like pluripotent state. At that point, researchers can coax the iSP cells into becoming whatever kind of cell they'd like. In the case of this Japanese study, the researchers created heart muscle cells from the iSP cells before placing them on small sheets. The patient, which suffers from ischemic cardiomyopathy, will be monitored for the next year. If all goes well, the researchers hope to conduct the same procedure on nine other people suffering from the same condition within the next three years.

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