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October 19, 2019 03:30 am

Unnatural Selection: the Eye-Opening Netflix Docuseries On Gene Editing

Dream McClinton from The Guardian writes about a new Netflix docuseries, called Unnatural Selection, that "explores the various forms of genetic engineering, as well as the societal and environmental implications of its research and use." An anonymous reader shares an excerpt from the report: Today, we are learning the language in which God created life," said then-president Bill Clinton, alongside the British prime minister, Tony Blair, in 2000. In the grainy archival clip, scientists and dignitaries had just mapped out the human genome, dissecting the complex science of biological being to code sequences of A, C, G and T in a style similar to binary computer code. But almost 20 years later, science has surpassed this once-unimaginable feat with the discovery of technology which can alter that genetic code. This zeitgeist-y innovation is the subject of a new Netflix series, Unnatural Selection, from film-makers Joe Egender and Leeor Kaufman, and explores the various forms of genetic engineering, as well as the societal and environmental implications of its research and use. The four-part docuseries delves into the burgeoning field of gene technology, made possible by the aforementioned human genome project and the discovery of the Clustered Regularly Interspaced Short Palindromic Repeats or Crispr. Co-discovered by Dr Jennifer Doudna, the gene serves a bit like "a molecular scalpel", she says, essentially removing and replacing gene material in a DNA strand. The technology makes it possible to modify genetics, giving it near unlimited biological potential, or as Salk Institute developmental biologist Professor Juan Izpuisua Belmonte puts it, "... rewriting the book of life." For Egender and Kaufman, the series had to tell the broader, more intricate story of genetic engineering, a story filled with great risk, benefits, consequences, emotions, sentiments and future, to better illuminate the field and further the discussion on the technology. "[M]any are depending on gene therapy treatment to change and possibly save lives," writes McClinton. "But, the series shows, the treatments are expensive, with some emerging drugs costing over $500,000, and patients are often at the mercy of startup genetic therapy companies who choose to weigh the 'meaning' of the treatment versus the cost for the patient, leaving many to fight their insurance companies for the cost of treatment."

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