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August 15, 2019 07:00 am

Scientists Reverse Aging Process In Rat Brain Stem Cells

Scientists who discovered aging appears to be related to the stiffness of the environment where cells live have reversed the process in rat brain stem cells. Newsweek reports: Researchers studied oligodendrocyte progenitor cells (OPCs) in young and old rat brains, and found they were affected by stiffness in the organ caused by aging. These stem cells, meaning they can turn into other types of cell, are found in the central nervous system. Researchers studied oligodendrocyte progenitor cells (OPCs) in young and old rat brains, and found they were affected by stiffness in the organ caused by aging. These stem cells, meaning they can turn into other types of cell, are found in the central nervous system. Kevin Chalut, a biophysicist at the University of Cambridge and co-author of the study published in the journal Nature told Newsweek: "The study tells us that aging, at least for stem cells we studied, is not driven by anything intrinsic to the cell. It is instead driven by the environment. This was already known to be a factor, but the true significance here is to show that it is the stiffness of the environment alone that drives the aging of the stem cells. "This is rather remarkable because it suggests an entirely new way of thinking about what controls aging in stem cells, and furthermore, since stiffness is a single factor from the environment, it suggest a means to straightforwardly reverse aging in stem cells'" Chalut explained.

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