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May 10, 2019 01:00 pm

Yet More Research Links Appendectomies and Parkinson's Disease

An anonymous reader quotes a report from Gizmodo: Last October, researchers studied population data from more than a million Swedish residents and found that people who had their appendix removed were slightly less likely to develop Parkinson's. But other research has shown that there were no clear link between the two events. So Gregory Cooper and his team at Case Western Reserve University in Ohio decided to look with an even bigger microscope. They studied the electronic health records of more than 62 million Americans. Contrary to the October study, though, they spotted an increased risk of Parkinson's among those who had their appendix removed, roughly three times higher. And while Parkinson's starts becoming much more common in old age, a consistent added risk from appendix removal was even seen in those who developed it younger and across different ethnicities. "This is the largest study to date that's looked at this," Cooper told Gizmodo by phone this week. "And it's the most generalizable to the overall population, we think." Cooper went on to say that this doesn't mean people shouldn't get an appendectomy if they need it: "Even with that threefold risk, it was still less than 1 percent of individuals who had an appendectomy and went on to develop Parkinson's. So in the grand scheme of things, it's a very low risk, and it shouldn't dissuade anyone from getting an appendectomy."

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