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October 1, 2017 10:00 am

Should Zambia Allow The Testing of Genetically-Modified Mosquitoes?

More than 400,000 lives are lost every year to malaria, reports the New York Post. But Thursday Science published two new studies on promisings ways to fight malaria -- with genetic engineering.The first study focused on whether mosquitoes that have been genetically modified to be more resistant to the malaria-causing parasite would become weaker and less able to mate and breed... The study, led by mosquito vector biologist George Dimopoulos, found that one type of genetically modified mosquito not only bred well, but became more attractive to normal mosquitoes... Within one generation, the mosquito population was becoming 90 percent genetically modified... The results suggest the genetically modified mosquitoes would not just thrive but could possibly drive their genetic immunity to the malaria parasite into mosquito populations to which they are introduced. The second study published Thursday uses genetic modification of bacteria found inside mosquitoes to fight malaria. Researchers genetically modified a type of bacteria, which caused it to secrete a substance inside the mosquitoes' gut that kills off the malaria-causing parasite before it can develop properly... the genetically modified versions of the bacteria automatically spread to offspring in generation after generation, the researchers found. The next step for both approaches -- the genetically modified mosquitoes and bacteria -- is to test if they work outside the lab in conditions simulating nature. Johns Hopkins has built a "mosquito house" research facility in Zambia designed specifically for such experiments... But the researchers must first convince the Zambian government to allow their genetically modified subjects into its borders.

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