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December 2, 2011 04:05 pm

Gene Therapy Approach 'Completely' Protects Mice From HIV Infection


Pierre Bezukhov writes "Scientists from the California Institute of Technology have come up with a gene therapy approach that has proven effective in protecting mice (with humanized immune systems) against HIV infections. They used a genetically altered virus to infect muscles cells and deliver DNA codes of potent antibodies isolated from the blood of human HIV victims (abstract). The muscle cells then began to manufacture the antibodies in quantities that proved 'completely protective' against HIV infection. By contrast, traditional vaccines have not worked against HIV, as scientists have failed to find a molecule that induces the immune system to produce enough potent antibodies. The difficulties stem from the fact that HIV disguises some of its external structures from the antibodies."

Read more of this story at Slashdot.


Original Link: http://rss.slashdot.org/~r/Slashdot/slashdot/~3/N0BQIAslyYU/gene-therapy-approach-completely-protects-mice-from-hiv-infection

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